With 1 in 5 seniors struggling to open traditional medication packaging, Keystone Folding Box Co., a global leader in pharmaceutical paperboard solutions, introduces Key-Pak Plus.

This innovative addition to the Key-Pak line combines senior-friendly accessibility with the highest U.S. child-resistant rating (F=1) in a sleek carton-and-blister format. Tested under U.S. protocols (16 CFR 1700.20), Key-Pak Plus earned top marks for non-reclosable CR designs and a 100 per cent pass rate in senior-friendly testing, aligning with global accessibility standards like ISO 17480 (guidelines for packaging usable by all, including those with limited dexterity).

Designed for oral solid dose (OSD) medications, Key-Pak Plus supports both thermoformed and cold-formed blisters, offering a cost-efficient solution that enhances patient adherence and protects medication integrity. Its intuitive push-through indicators (visual cues for correct dispensing) and guided dispensing mechanism (a structured path for blister removal) help reduce dosing errors, improving safety and treatment success for seniors. It’s ideal for clinical trials, physician samples and commercial packaging for brand and generic drugs.

Three core advantages for pharmaceutical manufacturers

Safety & global readiness

  • Achieves F=1 child resistance under U.S. protocol 16 CFR 1700.20 — the highest rating for non-reclosable packaging, ensuring no child access
  • 100 per cent pass rate in U.S. senior-friendly testing, meeting ISO 17480 standards for accessibility in global markets
  • Durable paperboard sleeve safeguards light-sensitive and fragile medications during transport

Brand & patient engagement

  • Expansive billboard space for branding, multilingual labelling, and clear patient instructions
  • Smooth “zipper” dispensing action allows clean, precise blister removal, easing access for seniors with limited dexterity
  • Enhances patient experience, reducing frustration and supporting consistent medication use

Efficiency & cost advantages

  • Cost-effective paperboard design balances safety and performance
  • Compatible with both thermoformed and cold-formed blisters
  • Short sealing times and reduced heat exposure protect sensitive products
  • Stackable, self-contained format simplifies distribution and storage

Supply chain advantage and availability

Manufactured entirely in the United States, Key-Pak Plus ensures consistent quality and reliable lead times, offering pharmaceutical companies a stable supply chain in a volatile global market.

Key-Pak Plus is available in various sizes to suit diverse OSD formats. Keystone Folding Box Co. provides engineering support and packaging line integration for pharmaceutical partners worldwide.

“Key-Pak Plus empowers seniors to manage their medications with confidence while keeping children safe,” said Ward Smith, spokesperson for Keystone Folding Box Co. “It’s a game-changer for manufacturers seeking safe, accessible and efficient packaging that meets global standards.”

For more information visit: www.keyboxco.com.

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